Mississippi Boy Recovers After Rare Immune Condition and Stem Cell Transplant
An 11-year-old boy from Gulfport, Mississippi, named Peyton Stewart, has overcome a rare condition called STAT1 gain-of-function, which caused his immune system to attack his red blood cells. He received a lifesaving stem cell transplant, with his older brother serving…

Champaign Urbana & Springfield Decatur, IL, October 3, 2026 —
Peyton Stewart, an 11-year-old resident of Gulfport, Mississippi, has successfully recovered from STAT1 gain-of-function, a rare medical condition that led his own immune system to target his red blood cells.
The condition required a significant medical intervention, and Peyton received a lifesaving stem cell transplant. His older brother generously served as the donor for the procedure.
The transplant was performed at Manning Family Children’s Hospital. Approximately one year following the successful operation, Peyton has reached a milestone in his recovery. He recently marked this occasion and is now looking ahead to pursuing his personal aspirations.
STAT1 gain-of-function is a condition characterized by an overactive immune response. In Peyton’s case, this overactivity resulted in his immune system attacking his body’s red blood cells, a critical component for oxygen transport throughout the body. The stem cell transplant was crucial to establishing a new, healthy immune system capable of functioning correctly.
The support and contribution of his older brother as the donor were instrumental in the success of the treatment. The collaborative efforts at Manning Family Children’s Hospital provided the medical expertise and care necessary for Peyton’s recovery journey.
Celebrating one year post-transplant signifies a critical period of recovery and healing for Peyton. This milestone allows him and his family to look towards the future with optimism as he prepares to engage in activities and pursue the dreams he has for his life.
Story summarized from the original created by Thanh Truong, Gray News staff on www.wandtv.com, see more information here.
Media gallery
